Apoptosis inducing activity of Fucoidan in HCT-15 Colon Carcinoma Cells
Fucoidan has been shown to activate caspases and mitochondria-mediated apoptosis pathways, leading to the destruction of colon cancer cells.
Colon Cancer
Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
Fucoidan may suppress VEGF, which tumors use to develop blood vessels, potentially “starving” the tumor of nutrients.
Colon Cancer
Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
Some studies show fucoidan enhances the effects of chemotherapy drugs like 5-FU and oxaliplatin while reducing side effects.
Lung Cancer
Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
Inhibition of lung cancer cell growth and metastasis via modulation of PI3K-Akt-mTOR pathways.
Lung Cancer
Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation
Research on the role of Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation.
Antitumor effect and molecular mechanism of fucoidan in NSCLC
Fucoidan represents an ideal therapeutic agent for non-small cell lung cancer (NSCLC).
Lung Cancer
Fucoidan enhances the effect of chemotherapeutic drug against drug-resistant lung cancer cells
Synergy with chemotherapy for drug-resistant lung cancer cells.
Liver Cancer
Study of Oligo-Fucoidan in Advanced Hepatocellular Carcinoma (HCC)
First completed randomized, double-blind, placebo-controlled trial in HCC, comparing oligo-fucoidan alongside standard care.
Liver Cancer
Fucoidan Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma via the p38 MAPK/ERK and PI3K/Akt Signal Pathways
Induction of apoptosis and inhibition of proliferation via MAPK/ERK and PI3K/Akt pathways.